Opportunity Information: Apply for PA 18 396
The Mentored Quantitative Research Development Award (Parent K25 - No Independent Clinical Trials), funding opportunity number PA 18-396, is an NIH career development grant designed to bring skilled quantitative scientists and engineers into research areas that clearly align with NIH priorities in health and disease. The core idea is to support professionals who have strong track records in quantitative disciplines but whose past work has not been primarily centered on biomedical, behavioral, or clinical health questions. Through a structured, mentored experience, the K25 aims to help these investigators pivot their expertise toward NIH-relevant problems and build a sustainable trajectory in health-focused research.
A defining feature of this opportunity is that it provides financial support and protected time for a period of supervised study and research. In practice, that means the award is intended to buy down other professional obligations so the awardee can devote meaningful effort to training and mentored research. The emphasis is on development: strengthening the applicant's ability to apply advanced quantitative approaches to health and disease topics while working closely with one or more established mentors. The program particularly targets people coming from fields such as mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry, and a broad range of engineering backgrounds. The expectation is that the awardee will integrate their existing technical strengths with biomedical or public health questions, often by learning new domain knowledge, building collaborations, and producing research outputs that demonstrate the value of quantitative methods in addressing health-related challenges.
This specific K25 parent announcement explicitly excludes independent clinical trials, which is important for project planning. Applicants should understand this as a boundary around the type of research activities the career development plan can support. While the broader NIH ecosystem includes clinical trial mechanisms, this version of the K25 is oriented toward mentored research and training activities that do not involve leading an independent clinical trial. The focus remains on acquiring health-relevant research experience under mentorship and producing a body of work that positions the investigator for later independence in NIH-relevant research.
Eligibility for applying organizations is broad and includes many types of U.S.-based entities. Eligible applicants listed for this opportunity include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education when specified); for-profit organizations other than small businesses; and small businesses. The announcement also highlights additional eligible applicant categories that NIH seeks to include, such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal government agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
Foreign eligibility is limited and spelled out clearly. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply directly, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as NIH defines them in the NIH Grants Policy Statement, are allowed. In other words, the applicant organization must be eligible and domestic, but certain project elements may include foreign components when permitted under NIH policy and justified scientifically.
From an administrative standpoint, this is a discretionary grant program administered by the National Institutes of Health. It is categorized under a broad set of funding activity areas that include education, environment, food and nutrition, health, and income security and social services. The opportunity is associated with multiple CFDA numbers, reflecting participation across different NIH institutes, centers, and program areas: 93.113, 93.121, 93.173, 93.233, 93.273, 93.279, 93.286, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.855, 93.859, 93.865, and 93.866. The record indicates a creation date of November 22, 2017, and an original closing date of January 7, 2019. The provided source data does not specify an award ceiling or expected number of awards, which suggests applicants would need to consult the full NIH funding announcement and related institute guidance for budget structures, allowable costs, and typical award levels.
Overall, this K25 opportunity is best understood as a mentored bridge for established quantitative professionals to reposition their careers toward NIH-relevant health research. It supports a deliberate transition: pairing rigorous quantitative training and methods development with biomedical or public health mentorship, so the awardee can demonstrate impact in health-focused research and move toward long-term independence without proposing an independent clinical trial as part of this award.Apply for PA 18 396
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Mentored Quantitative Research Development Award (Parent K25 - No Independent Clinical Trials)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.233, 93.273, 93.279, 93.286, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.855, 93.859, 93.865, 93.866.
- This funding opportunity was created on 2017-11-22.
- Applicants must submit their applications by 2019-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants who have applied for this opportunity (PA 18 396) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIH Pathway to Independence Award (Parent K99/R00 - Independent Clinical Trial Not Allowed) Apply for PA 18 398 Funding Number: PA 18 398 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 18 484 Funding Number: PA 18 484 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed) Apply for PA 18 504 Funding Number: PA 18 504 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $300,000 |
| Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 517 Funding Number: PA 18 517 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 18 574 Funding Number: PA 18 574 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 18 575 Funding Number: PA 18 575 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 586 Funding Number: PA 18 586 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp - Clinical Trial Optional) Apply for PA 18 591 Funding Number: PA 18 591 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 18 589 Funding Number: PA 18 589 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Change of Grantee Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 18 590 Funding Number: PA 18 590 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed ) Apply for PA 18 592 Funding Number: PA 18 592 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 18 648 Funding Number: PA 18 648 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) Apply for PA 18 658 Funding Number: PA 18 658 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31) Apply for PA 18 666 Funding Number: PA 18 666 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 668 Funding Number: PA 18 668 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 18 671 Funding Number: PA 18 671 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 18 670 Funding Number: PA 18 670 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA)Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 673 Funding Number: PA 18 673 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 18 740 Funding Number: PAR 18 740 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements for Research on Dietary Supplements (Admin. Supp.- Clinical Trial Not Allowed) Apply for PA 18 817 Funding Number: PA 18 817 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $100,000 |
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