Opportunity Information: Apply for PAR 22 118
The International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed), funding opportunity number PAR-22-118, is a National Institutes of Health (NIH) discretionary grant program designed to support education-focused efforts (not clinical trials) that strengthen research ethics capacity in low- and middle-income countries. The core purpose is to develop and deliver education programs that give scientists, health professionals, and academic leaders a deep, practical understanding of ethical principles, oversight processes, and policy frameworks relevant to international clinical and public health research. In practice, this means building training and curriculum initiatives that help participants navigate real-world ethical challenges that arise when conducting or overseeing research across different countries, health systems, regulatory environments, and cultural contexts.
This opportunity uses the NIH R25 mechanism, which is typically aimed at structured educational activities such as curriculum development, course design, educational materials, and training programs that build knowledge and skills in a targeted area. The emphasis here is specifically on research ethics education tied to international clinical and public health research, with the intended outcome of better-prepared professionals who can contribute to ethically sound study design, review, and conduct. Because the notice explicitly states "Clinical Trial Not Allowed," applicants should propose educational and curriculum activities rather than interventional studies that would meet the definition of a clinical trial.
Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and certain other organizations, reflecting an intent to involve universities and academic partners that can build sustainable training programs. The announcement also highlights additional eligible applicant categories that include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). This signals NIH interest in broad institutional participation and in leveraging the strengths of diverse U.S.-based educational institutions that may have strong community ties, global partnerships, or experience in capacity-building and workforce development.
From an administrative standpoint, the sponsoring agency is the National Institutes of Health, and the funding activity falls under the health category, with CFDA numbers 93.172, 93.855, and 93.989 listed for program tracking. The opportunity was created on 2022-03-10 and had an original closing date of 2024-06-06. The listed award ceiling is $230,000, which functions as the upper limit for the amount that can be awarded under this announcement. The posting notes "ExpectedAwards:" but does not provide a specific number in the source data provided, so applicants would typically look to the full funding announcement for details on anticipated award volume, project periods, and budgeting expectations.
Overall, PAR-22-118 is best understood as a capacity-building education grant aimed at improving the quality and consistency of international research ethics understanding and practice, particularly in settings where research infrastructure and ethics training opportunities may be limited. It supports programs that can train individuals who will participate in, oversee, or teach about ethical conduct in international clinical and public health research, thereby helping strengthen ethical review, institutional practices, and policy-informed decision-making in global health research environments.Apply for PAR 22 118
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172, 93.855, 93.989.
- This funding opportunity was created on 2022-03-10.
- Applicants must submit their applications by 2024-06-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $230,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
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Frequently Asked Questions (FAQs)
What is the International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)?
It is a National Institutes of Health (NIH) discretionary grant program that supports education-focused efforts to strengthen research ethics capacity in low- and middle-income countries. The program centers on developing and delivering education programs and curriculum initiatives that build practical understanding of ethical principles, oversight processes, and policy frameworks relevant to international clinical and public health research.
What is the funding opportunity number for this program?
The funding opportunity number is PAR-22-118.
Which agency sponsors this grant opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What is the main purpose of PAR-22-118?
The main purpose is capacity-building through research ethics education. The opportunity supports programs that train scientists, health professionals, and academic leaders to better understand and apply ethical principles and oversight practices in real-world international clinical and public health research settings.
What types of activities does the NIH R25 mechanism typically support in this opportunity?
This R25 opportunity emphasizes structured educational activities such as curriculum development, course design, educational materials, and training programs that build knowledge and skills in international research ethics.
Does this funding opportunity allow clinical trials?
No. The notice explicitly states "Clinical Trial Not Allowed," so applicants should propose educational and curriculum activities rather than interventional studies that would meet the definition of a clinical trial.
What kinds of projects are a good fit for this opportunity?
Projects that develop or strengthen education programs in research ethics tied to international clinical and public health research. This includes training and curriculum initiatives that prepare participants to navigate ethical challenges arising across countries, health systems, regulatory environments, and cultural contexts.
Who is the intended audience for the training supported by this grant?
The intended audience includes scientists, health professionals, and academic leaders who will participate in, oversee, or teach about ethical conduct in international clinical and public health research.
What outcomes is NIH aiming for through this program?
The intended outcome is better-prepared professionals who can contribute to ethically sound study design, review, and conduct. Over time, the broader goal is stronger ethical review, improved institutional practices, and more policy-informed decision-making in global health research environments.
What geographic or capacity-building focus is emphasized?
The opportunity emphasizes strengthening research ethics capacity in low- and middle-income countries, particularly where research infrastructure and ethics training opportunities may be limited.
Which organizations are eligible to apply?
Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and certain other organizations.
Are any specific categories of U.S. institutions highlighted as eligible applicants?
Yes. The announcement highlights additional eligible applicant categories including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and Tribally Controlled Colleges and Universities (TCCUs).
What does the emphasis on diverse institution types suggest about NIH priorities?
It suggests an interest in broad institutional participation and leveraging the strengths of diverse U.S.-based educational institutions, including those with strong community ties, global partnerships, or experience in capacity-building and workforce development.
What is the award ceiling for PAR-22-118?
The listed award ceiling is $230,000, which functions as the upper limit for the amount that can be awarded under this announcement.
How many awards does NIH expect to make?
The posting notes "ExpectedAwards:" but does not provide a specific number in the information provided. Applicants would typically check the full funding announcement for anticipated award volume and related details.
What is the CFDA information associated with this opportunity?
The CFDA numbers listed for program tracking are 93.172, 93.855, and 93.989.
What category does this funding opportunity fall under?
The funding activity falls under the health category.
When was this opportunity created?
The opportunity was created on 2022-03-10.
What was the original closing date listed for this opportunity?
The original closing date was 2024-06-06.
What does "education-focused" mean in the context of this opportunity?
It means the funded work should focus on developing and delivering training, curricula, and related educational materials to build research ethics knowledge and skills, rather than conducting research studies (especially not clinical trials).
What kinds of real-world ethics challenges is the program meant to prepare participants for?
It is meant to prepare participants to handle ethical challenges that arise when conducting or overseeing research across different countries, health systems, regulatory environments, and cultural contexts, within international clinical and public health research.
Is this grant intended to improve ethics oversight and decision-making?
Yes. A key aim is strengthening ethical review and institutional practices, and supporting policy-informed decision-making in global health research environments through improved ethics education and training.
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