International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed) | PAR 22 118

Opportunity Information: Apply for PAR 22 118

The International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed), funding opportunity number PAR-22-118, is a National Institutes of Health (NIH) discretionary grant program designed to support education-focused efforts (not clinical trials) that strengthen research ethics capacity in low- and middle-income countries. The core purpose is to develop and deliver education programs that give scientists, health professionals, and academic leaders a deep, practical understanding of ethical principles, oversight processes, and policy frameworks relevant to international clinical and public health research. In practice, this means building training and curriculum initiatives that help participants navigate real-world ethical challenges that arise when conducting or overseeing research across different countries, health systems, regulatory environments, and cultural contexts.

This opportunity uses the NIH R25 mechanism, which is typically aimed at structured educational activities such as curriculum development, course design, educational materials, and training programs that build knowledge and skills in a targeted area. The emphasis here is specifically on research ethics education tied to international clinical and public health research, with the intended outcome of better-prepared professionals who can contribute to ethically sound study design, review, and conduct. Because the notice explicitly states "Clinical Trial Not Allowed," applicants should propose educational and curriculum activities rather than interventional studies that would meet the definition of a clinical trial.

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and certain other organizations, reflecting an intent to involve universities and academic partners that can build sustainable training programs. The announcement also highlights additional eligible applicant categories that include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). This signals NIH interest in broad institutional participation and in leveraging the strengths of diverse U.S.-based educational institutions that may have strong community ties, global partnerships, or experience in capacity-building and workforce development.

From an administrative standpoint, the sponsoring agency is the National Institutes of Health, and the funding activity falls under the health category, with CFDA numbers 93.172, 93.855, and 93.989 listed for program tracking. The opportunity was created on 2022-03-10 and had an original closing date of 2024-06-06. The listed award ceiling is $230,000, which functions as the upper limit for the amount that can be awarded under this announcement. The posting notes "ExpectedAwards:" but does not provide a specific number in the source data provided, so applicants would typically look to the full funding announcement for details on anticipated award volume, project periods, and budgeting expectations.

Overall, PAR-22-118 is best understood as a capacity-building education grant aimed at improving the quality and consistency of international research ethics understanding and practice, particularly in settings where research infrastructure and ethics training opportunities may be limited. It supports programs that can train individuals who will participate in, oversee, or teach about ethical conduct in international clinical and public health research, thereby helping strengthen ethical review, institutional practices, and policy-informed decision-making in global health research environments.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "International Research Ethics Education and Curriculum Development Award (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172, 93.855, 93.989.
• This funding opportunity was created on 2022-03-10.
• Applicants must submit their applications by 2024-06-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $230,000.00 in funding.
• Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.

Apply for PAR 22 118

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