Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States | CDC RFA DP 25 0024

Opportunity Information: Apply for CDC RFA DP 25 0024

The Centers for Disease Control and Prevention (CDC), through the National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), is offering a cooperative agreement called "Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States" (Funding Opportunity Number CDC RFA DP 25 0024; CFDA 93.377). The grant is designed to close a persistent gap: while chronic disease prevention and control efforts have improved across much of the United States over the last few decades, comparable progress has not occurred at the same pace in U.S. territories and the freely associated states. The overall public health backdrop is substantial, with chronic disease affecting a majority of U.S. adults and representing a major driver of healthcare spending. This opportunity is meant to help territories and freely associated states strengthen long-term, practical chronic disease work using integrated and evidence-based approaches.

The geographic focus is specific and limited to jurisdictions in American Samoa, the Commonwealth of the Northern Mariana Islands (CNMI), the Federated States of Micronesia (FSM), Guam, Puerto Rico, the Republic of the Marshall Islands (RMI), the Republic of Palau, and the U.S. Virgin Islands. CDC highlights that these island jurisdictions face distinct and compounding barriers that can make chronic disease prevention and management more difficult than on the mainland, including higher disease burden, populations spread across islands and remote areas, limited infrastructure, diverse cultures and languages, heightened exposure to natural disasters, strained healthcare delivery systems, and high healthcare costs. The intent is to support programs that fit these real-world conditions rather than assuming a one-size-fits-all approach.

Programmatically, the NOFO aims to reduce disability and premature death related to chronic diseases by lowering the prevalence of modifiable risk factors. It emphasizes a coordinated, integrated strategy rather than isolated projects. The core focus areas called out in the announcement include preventing and reducing tobacco use and exposure to secondhand smoke, preventing and managing diabetes, and improving oral health outcomes where disparities are present. In practice, this means applicants should be prepared to implement interventions with a strong evidence base, with activities designed to measurably improve population health indicators tied to these chronic disease priorities.

Structurally, the funding is organized into two parts. First, there is a required Core Component, which is the main body of work and is expected to use evidence-based strategies to promote health and reduce chronic disease risk across the jurisdiction. Second, there is an optional Oral Health Component that is competitive; applicants may choose to apply for it, and it focuses specifically on oral disease through evidence-based interventions and practices. The way the NOFO is framed suggests that oral health is both a standalone priority and also connected to broader chronic disease outcomes, with applicants expected to address disparities and implement proven approaches rather than pilot-only or purely educational campaigns without measurable impact.

A major compliance and readiness requirement involves data access and reporting. CDC makes clear that recipients must be able to access required surveillance and health system data and submit it to CDC to demonstrate progress on performance measures. If an applicant is not the Department or Ministry of Health in the jurisdiction where the work will occur, the applicant must include a formal memorandum of understanding (MOU) or memorandum of agreement (MOA) with the relevant Department or Ministry of Health. That agreement must explicitly state that the health authority will provide access to surveillance and health system data, grant the applicant authority to submit those data to CDC, and collaborate to ensure data submitted to CDC are complete. The required document must be uploaded with the application as an attachment labeled "MOUDataAccess" in Grants.gov, making this a practical gatekeeping item for non-health-ministry applicants.

The NOFO also includes a strict location and implementation requirement. Applicants must provide proof that they are located in, and can implement the program in, one of the listed U.S. territories or freely associated states. Acceptable proof can include documentation showing the applicant is a territorial government or a bona fide agent operating in that jurisdiction. A bona fide agent, as described in the announcement, is an agency or organization formally recognized by the jurisdiction as eligible to apply on its behalf under the jurisdiction's eligibility rules. Applicants applying as a territorial government or as a bona fide agent of a jurisdiction or local government must attach documentation as "Evidence of Location" when submitting through Grants.gov, signaling that CDC expects to verify local standing and capacity to operate on the ground.

From an administrative standpoint, this is a discretionary cooperative agreement, which typically means CDC expects substantial involvement with recipients beyond simply issuing funds, such as technical assistance, coordination, and shared planning around performance monitoring. The opportunity anticipates up to 8 awards, with an award ceiling of $1,400,000. The original closing date listed is January 15, 2025, and the opportunity was created on November 15, 2024. Eligible applicant types are broad on paper (including various levels of government, higher education institutions, nonprofits with or without 501(c)(3) status, for-profit organizations, small businesses, tribal entities, and others), but the practical eligibility is constrained by the location requirement and the need to operate within one of the named island jurisdictions, plus the data-sharing agreement requirement when the applicant is not the health ministry itself.

Overall, the grant is aimed at helping island jurisdictions build and sustain a coordinated chronic disease prevention and management system with measurable outcomes, focusing on tobacco control, diabetes prevention and management, and optionally oral health disparities. It places strong emphasis on evidence-based interventions, jurisdiction-specific implementation, and reliable data reporting arrangements, reflecting CDC's priority to link funding to documented performance and durable public health capacity in the territories and freely associated states.

• The Centers for Disease Control - NCCDPHP in the health sector is offering a public funding opportunity titled "Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.377.
• This funding opportunity was created on 2024-11-15.
• Applicants must submit their applications by 2025-01-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,400,000.00 in funding.
• The number of recipients for this funding is limited to 8 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.

Apply for CDC RFA DP 25 0024

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