Opportunity Information: Apply for CDC RFA DP 25 0024

The Centers for Disease Control and Prevention (CDC), through the National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), is offering a cooperative agreement called "Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States" (Funding Opportunity Number CDC RFA DP 25 0024; CFDA 93.377). The grant is designed to close a persistent gap: while chronic disease prevention and control efforts have improved across much of the United States over the last few decades, comparable progress has not occurred at the same pace in U.S. territories and the freely associated states. The overall public health backdrop is substantial, with chronic disease affecting a majority of U.S. adults and representing a major driver of healthcare spending. This opportunity is meant to help territories and freely associated states strengthen long-term, practical chronic disease work using integrated and evidence-based approaches.

The geographic focus is specific and limited to jurisdictions in American Samoa, the Commonwealth of the Northern Mariana Islands (CNMI), the Federated States of Micronesia (FSM), Guam, Puerto Rico, the Republic of the Marshall Islands (RMI), the Republic of Palau, and the U.S. Virgin Islands. CDC highlights that these island jurisdictions face distinct and compounding barriers that can make chronic disease prevention and management more difficult than on the mainland, including higher disease burden, populations spread across islands and remote areas, limited infrastructure, diverse cultures and languages, heightened exposure to natural disasters, strained healthcare delivery systems, and high healthcare costs. The intent is to support programs that fit these real-world conditions rather than assuming a one-size-fits-all approach.

Programmatically, the NOFO aims to reduce disability and premature death related to chronic diseases by lowering the prevalence of modifiable risk factors. It emphasizes a coordinated, integrated strategy rather than isolated projects. The core focus areas called out in the announcement include preventing and reducing tobacco use and exposure to secondhand smoke, preventing and managing diabetes, and improving oral health outcomes where disparities are present. In practice, this means applicants should be prepared to implement interventions with a strong evidence base, with activities designed to measurably improve population health indicators tied to these chronic disease priorities.

Structurally, the funding is organized into two parts. First, there is a required Core Component, which is the main body of work and is expected to use evidence-based strategies to promote health and reduce chronic disease risk across the jurisdiction. Second, there is an optional Oral Health Component that is competitive; applicants may choose to apply for it, and it focuses specifically on oral disease through evidence-based interventions and practices. The way the NOFO is framed suggests that oral health is both a standalone priority and also connected to broader chronic disease outcomes, with applicants expected to address disparities and implement proven approaches rather than pilot-only or purely educational campaigns without measurable impact.

A major compliance and readiness requirement involves data access and reporting. CDC makes clear that recipients must be able to access required surveillance and health system data and submit it to CDC to demonstrate progress on performance measures. If an applicant is not the Department or Ministry of Health in the jurisdiction where the work will occur, the applicant must include a formal memorandum of understanding (MOU) or memorandum of agreement (MOA) with the relevant Department or Ministry of Health. That agreement must explicitly state that the health authority will provide access to surveillance and health system data, grant the applicant authority to submit those data to CDC, and collaborate to ensure data submitted to CDC are complete. The required document must be uploaded with the application as an attachment labeled "MOUDataAccess" in Grants.gov, making this a practical gatekeeping item for non-health-ministry applicants.

The NOFO also includes a strict location and implementation requirement. Applicants must provide proof that they are located in, and can implement the program in, one of the listed U.S. territories or freely associated states. Acceptable proof can include documentation showing the applicant is a territorial government or a bona fide agent operating in that jurisdiction. A bona fide agent, as described in the announcement, is an agency or organization formally recognized by the jurisdiction as eligible to apply on its behalf under the jurisdiction's eligibility rules. Applicants applying as a territorial government or as a bona fide agent of a jurisdiction or local government must attach documentation as "Evidence of Location" when submitting through Grants.gov, signaling that CDC expects to verify local standing and capacity to operate on the ground.

From an administrative standpoint, this is a discretionary cooperative agreement, which typically means CDC expects substantial involvement with recipients beyond simply issuing funds, such as technical assistance, coordination, and shared planning around performance monitoring. The opportunity anticipates up to 8 awards, with an award ceiling of $1,400,000. The original closing date listed is January 15, 2025, and the opportunity was created on November 15, 2024. Eligible applicant types are broad on paper (including various levels of government, higher education institutions, nonprofits with or without 501(c)(3) status, for-profit organizations, small businesses, tribal entities, and others), but the practical eligibility is constrained by the location requirement and the need to operate within one of the named island jurisdictions, plus the data-sharing agreement requirement when the applicant is not the health ministry itself.

Overall, the grant is aimed at helping island jurisdictions build and sustain a coordinated chronic disease prevention and management system with measurable outcomes, focusing on tobacco control, diabetes prevention and management, and optionally oral health disparities. It places strong emphasis on evidence-based interventions, jurisdiction-specific implementation, and reliable data reporting arrangements, reflecting CDC's priority to link funding to documented performance and durable public health capacity in the territories and freely associated states.

  • The Centers for Disease Control - NCCDPHP in the health sector is offering a public funding opportunity titled "Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.377.
  • This funding opportunity was created on 2024-11-15.
  • Applicants must submit their applications by 2025-01-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,400,000.00 in funding.
  • The number of recipients for this funding is limited to 8 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
Apply for CDC RFA DP 25 0024

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FAQs: CDC Cooperative Agreement - Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States (CDC RFA DP 25 0024; CFDA 93.377)

1) What is this funding opportunity?

This opportunity is a CDC discretionary cooperative agreement offered through the National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) titled "Advancing Public Health Actions to Prevent and Control Chronic Disease in the U.S. Territories and Freely Associated States" (Funding Opportunity Number CDC RFA DP 25 0024; CFDA 93.377).

2) What problem is this grant intended to address?

The grant is intended to close a persistent gap in chronic disease prevention and control progress. While many parts of the United States have made advances over the last few decades, comparable progress has not occurred at the same pace in U.S. territories and the freely associated states. The program is designed to strengthen long-term, practical, integrated chronic disease work in these jurisdictions using evidence-based approaches.

3) Which jurisdictions are eligible based on geographic focus?

The geographic focus is limited to the following U.S. territories and freely associated states: American Samoa; the Commonwealth of the Northern Mariana Islands (CNMI); the Federated States of Micronesia (FSM); Guam; Puerto Rico; the Republic of the Marshall Islands (RMI); the Republic of Palau; and the U.S. Virgin Islands.

4) Why does CDC focus specifically on territories and freely associated states?

CDC highlights that these island jurisdictions often face distinct and compounding barriers that can make chronic disease prevention and management more difficult than on the mainland, including higher disease burden; populations spread across islands and remote areas; limited infrastructure; diverse cultures and languages; heightened exposure to natural disasters; strained healthcare delivery systems; and high healthcare costs. The intent is to support programs that fit these real-world conditions rather than applying a one-size-fits-all approach.

5) What are the main program goals?

The NOFO aims to reduce disability and premature death related to chronic diseases by lowering the prevalence of modifiable risk factors. It emphasizes a coordinated, integrated strategy rather than isolated projects, with activities expected to measurably improve population health indicators tied to the chronic disease priorities in the announcement.

6) What chronic disease focus areas are emphasized?

The core focus areas called out include: preventing and reducing tobacco use and exposure to secondhand smoke; preventing and managing diabetes; and improving oral health outcomes where disparities are present.

7) Does the opportunity require an integrated approach, or can applicants propose separate stand-alone projects?

The NOFO emphasizes a coordinated, integrated strategy rather than isolated projects. Applicants should be prepared to implement interventions with a strong evidence base and design activities that connect to measurable outcomes and performance measures.

8) How is the funding structured?

Funding is organized into two parts: (1) a required Core Component, which is the main body of work using evidence-based strategies to promote health and reduce chronic disease risk across the jurisdiction; and (2) an optional Oral Health Component that is competitive and focuses specifically on oral disease through evidence-based interventions and practices.

9) Is the Oral Health Component required?

No. The Oral Health Component is optional and competitive. Applicants may choose to apply for it in addition to the required Core Component.

10) What is expected for oral health activities if an applicant chooses to apply for the optional component?

The optional Oral Health Component is framed as focusing on oral disease through evidence-based interventions and practices, with attention to disparities. The NOFO indicates CDC expects proven approaches and measurable impact rather than activities that are solely pilots or purely educational campaigns without measurable outcomes.

11) What does "evidence-based" mean in the context of this NOFO?

Based on the NOFO description, applicants are expected to implement interventions with a strong evidence base and design activities that can demonstrate measurable improvements in population health indicators and performance measures tied to the program priorities.

12) What is a cooperative agreement, and what does it imply for CDC involvement?

This opportunity is a discretionary cooperative agreement. As described in the announcement summary, this typically means CDC expects substantial involvement with recipients beyond simply issuing funds, such as technical assistance, coordination, and shared planning around performance monitoring.

13) How many awards does CDC expect to make?

The opportunity anticipates up to 8 awards.

14) What is the maximum funding amount available per award?

The award ceiling is $1,400,000.

15) What is the application deadline?

The original closing date listed is January 15, 2025.

16) When was this funding opportunity created?

The opportunity was created on November 15, 2024.

17) Who is eligible to apply?

Eligible applicant types are broad on paper and include various levels of government, higher education institutions, nonprofits with or without 501(c)(3) status, for-profit organizations, small businesses, tribal entities, and others. However, practical eligibility is constrained by the location requirement (being located in and able to implement in one of the listed jurisdictions) and by data access and reporting requirements (including an MOU/MOA when the applicant is not the Department/Ministry of Health).

18) What proof is required to show an applicant is located in an eligible jurisdiction?

Applicants must provide proof that they are located in, and can implement the program in, one of the listed U.S. territories or freely associated states. Acceptable proof can include documentation showing the applicant is a territorial government or a bona fide agent operating in that jurisdiction. Applicants applying as a territorial government or as a bona fide agent must attach documentation as "Evidence of Location" when submitting through Grants.gov.

19) What is a "bona fide agent" in this NOFO?

A bona fide agent is described as an agency or organization formally recognized by the jurisdiction as eligible to apply on its behalf under the jurisdiction's eligibility rules.

20) What data access and reporting capabilities are required?

CDC states that recipients must be able to access required surveillance and health system data and submit it to CDC to demonstrate progress on performance measures.

21) What if the applicant is not the Department or Ministry of Health?

If the applicant is not the Department or Ministry of Health in the jurisdiction where the work will occur, the application must include a formal memorandum of understanding (MOU) or memorandum of agreement (MOA) with the relevant Department or Ministry of Health.

22) What must the MOU/MOA include?

The MOU/MOA must explicitly state that the health authority will: (1) provide access to surveillance and health system data; (2) grant the applicant authority to submit those data to CDC; and (3) collaborate to ensure data submitted to CDC are complete.

23) How should the required MOU/MOA be submitted with the application?

The required document must be uploaded with the application as an attachment labeled "MOUDataAccess" in Grants.gov.

24) Is the MOU/MOA requirement described as optional or mandatory for non-health-ministry applicants?

It is described as a practical gatekeeping requirement for applicants that are not the Department or Ministry of Health, because CDC requires the data access and submission authority necessary to report performance measures.

25) What kinds of outcomes does CDC expect recipients to demonstrate?

The NOFO emphasizes measurable improvement in population health indicators tied to chronic disease priorities and performance measures, supported by reliable surveillance and health system data access and reporting.

26) What are the main implementation expectations for island jurisdictions?

The opportunity is intended to support programs that fit the local conditions of the eligible island jurisdictions, including remote and dispersed populations, limited infrastructure, diverse cultures and languages, vulnerability to natural disasters, strained health systems, and high healthcare costs. The NOFO emphasizes practical, long-term work rather than approaches that assume mainland conditions.

27) What are the key compliance-related attachments mentioned in the NOFO summary?

Two specific application attachments are called out: (1) "MOUDataAccess" (required when the applicant is not the Department/Ministry of Health) and (2) "Evidence of Location" (required for applicants applying as a territorial government or as a bona fide agent of a jurisdiction or local government).

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